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When a man has both low testosterone and weight concerns, the initial treatment often targets the most pressing issue, says James Staheli, D.O., a family medicine doctor who specializes in hormone health

Key finding: ~5% body weight loss in 11 days, 35% white adipose tissue reduction , ~30% lower cholesterol with no change in food intake

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For example, healing can be hindered by increased tissue damage, via opposing effects of cytokines such as VEGF and TNF 160,161

In fact, unstimulated neutrophils and lymphocytes isolated from older adults patients accumulate greater amounts of ROS, present decreased SOD activity, and are less resistant to cell death compared to those cells obtained from young individuals (161)

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